After receiving her Ph.D. from Sophia University, she worked as a specially-appointed assistant professor at the Faculty of Science and Engineering, Sophia University, and as a specially-appointed researcher at the Institute for Solid State Physics, The University of Tokyo before assuming her current position at the Research organization for Information Science & Technology (RIST), a registered facility for the K computer and the Fugaku supercomputer, and a representative organization for the "Operation of HPCI" project commissioned by the Ministry of Education, Culture, Sports, Science and Technology (MEXT). She has been in her current position since 2015. She specializes in condensed matter theory. Currently, she oversees supporting the use of "Fugaku".

In March 1988, completed the doctoral program in the Department of Physics, Graduate School of Science, University of Tokyo. In April 1988, joined NTT Basic Research Laboratories. In January 2001, appointed as Associate Professor in the Department of Physics, University of Tsukuba. In October 2007, promoted to Professor at the Graduate School of Pure and Applied Sciences, University of Tsukuba. In May 2013, appointed as Professor at the Graduate School of Engineering, Nagoya University. In October 2015, became a Professor at the Institute of Materials and Systems for Sustainability, Nagoya University.

Since joining NTT, has been engaged in research on semiconductor process and device using computational science. Has made significant contributions to the market introduction of semiconductor devices through first-principles calculations. Always striving to make first-principles calculations truly beneficial for industry.

After obtaining a Doctor of Science degree from the University of Tsukuba, worked as a researcher at the National Institute of Advanced Industrial Science and Technology (AIST), followed by positions as an Assistant Professor at the University of Tsukuba and a Visiting Lecturer at the University of Tokyo. Later served as the Center Director at a company specializing in computational science and technology. In 2021, joined Quemix. Awarded the Gordon Bell Peak Performance Prize in 2011. Developer of the cloud-based material calculation platform, Quloud.

After receiving his PhD in engineering from the University of Tokyo, Matsushita worked as a researcher at the Max-Planck-Institut (Germany), an assistant professor at the University of Tokyo, a specially appointed lecturer at the Tokyo Institute of Technology, a specially appointed associate professor at the Tokyo Institute of Technology's Materials Information Center, and then the University of Tokyo. Specially appointed associate professor, Department of Physics, Faculty of Science.